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Air-polishing followed by ultrasonic calculus removal for the treatment of gingivitis: A 12-month, split-mouth randomized controlled clinical trial

Mensi M, Scotti E, Sordillo A, Dalè M, Calza S

International Journal of Dental Hygiene :1-10 (2024)

Abstract

Objective: To evaluate the advantages of a novel protocol involving full-mouth erythritol-powder air-polishing followed by ultrasonic calculus removal in the maintenance of patients treated for gingivitis, with a focus on time and comfort.

Methods: Systemically healthy patients with gingivitis were selected. Following a split-mouth design, quadrants 1–4 and 2–3 were randomly allocated to receive air-polishing followed by ultrasonic calculus removal following a protocol known as Guided Biofilm Therapy (GBT) or traditional full-mouth ultrasonic debridement followed by polishing with a rubber cup and prophylactic paste (US + P). Bleeding on probing (BoP) and the plaque index (PI) were collected at baseline (T0), 2 weeks (T1), 4 weeks (T2), 3 months (T3), and 6 months (T4) and 12 months (T5). Following the same randomization, prophylactic therapy was provided at 3 months (T3) and 6 months (T4). Clinical parameters, treatment time and patient comfort and satisfaction were evaluated.

Results: A total of 41 patients were selected, 39 completed the study. The clinical parameters were clinically satisfactory for both treatments at every time. At 4 months after treatment, GBT maintained significantly lower BoP and PI. GBT protocol required a significantly lower treatment time, especially at T3 and T4, when it saved 24.5% and 25.1% of the time, respectively. Both treatments were rated positively by most patients. However, GBT was perceived as more comfortable, and a higher number of patients preferred it.

Conclusion: No significant difference was observed between GBT and conventional ultrasonic debridement and rubber cup polishing in terms of BoP and PI levels. The GBT protocol allowed less time expenditure and higher patients' perceived comfort.

Keywords

air-polishingdental biofilmgingivitisoral hygieneplaque disclosing

Citazione

Mensi M, Scotti E, Sordillo A, Dalè M, Calza S. Air-polishing followed by ultrasonic calculus removal for the treatment of gingivitis: A 12-month, split-mouth randomized controlled clinical trial. International Journal of Dental Hygiene. 2024:1-10. doi: 10.1111/idh.12812

Study Highlights

Context: This is part 2 of the ERICO trial (part 1 published 2022, doi:10.1111/idh.12537), extending follow-up to 12 months with focus on maintenance therapy, time efficiency, and patient satisfaction.

Design: Double-blinded, split-mouth RCT | n=41 (39 completed) | 12-month follow-up | Ethics: ASST Spedali Civili di Brescia #2637

Population: Systemically healthy adults aged 20-40 with gingivitis (BoP >25%), ≥5 teeth/quadrant, non-smokers (<10 cig/day)

Interventions compared:

ProtocolSteps
GBTErythritol air-polishing (PLUS powder) → Site-specific ultrasonic (PS tip)
US+PFull-mouth ultrasonic debridement → Rubber cup + prophy paste (RDA 27)

Primary outcome: BoP change (non-inferiority design)

Key Results:

ParameterBaseline2 wk4 wk3 mo6 mo12 mo
BoP US+P56.7%7.3%14.8%14.1%15.0%10.2%
BoP GBT56.9%6.1%11.2%*15.8%16.6%11.5%
PI US+P65.3%14.6%14.7%17.2%22.9%19.5%
PI GBT65.0%14.9%12.7%*17.2%21.3%17.3%

*p<0.05 GBT vs US+P

Treatment Time:

TimepointUS+PGBTTime saved
Baseline20:3218:399.2%
3 months16:3812:3524.5%
6 months14:4511:0125.1%

All differences p<0.0001

Patient Preference (6 months):

  • Overall: 82.1% preferred GBT vs 5.1% US+P
  • Comfort: 94.9% preferred GBT
  • Quality perception: 79.5% rated GBT optimal vs 20.5% US+P
  • Zero discomfort: 35.9% GBT vs 0% US+P

Clinical significance:

  • GBT non-inferior to traditional prophylaxis for maintaining periodontal health over 12 months
  • ~25% chair time reduction translates to significant cost savings (€3-6/min chair time value)
  • Higher patient comfort may improve compliance with regular maintenance
  • Air-polishing before ultrasonics reduces time needed for calculus removal
  • Delayed biofilm repopulation may explain transient advantage at 4 weeks (Wolgin 2021 hypothesis)

Limitations: Young healthy population (20-40y), strict 3-month recall intervals, excludes patients with respiratory conditions

Related: Continues from Mensi 2022 (doi:10.1111/idh.12537) establishing GBT efficacy for gingivitis treatment